Результаты создания каталога прогностических генов-маркеров репродуктивного долголетия яичной птицы
Listing of the Prognostic Marker Genes Associated with the Reproductive Longevity in Layers
Laptev G.Y., Tiurina D.G., Yildyrym E.A., Filippova V.A., Ilyina L.A., Novikova N.I., Sokolova K.A., Savicheva A.A., Ponomareva E.S., Zaikin V.A., Morozov V.Y. (2025) Listing of the prognostic marker genes associated with the reproductive longevity in layers. Ptitsevodstvo, 74(12): 19-22. (in Russ.) doi: 10.33845/0033-3239-2025-74-12-19-22
Abstract. The search of genetic markers associated with the reproductive longevity in laying hens is necessary for the extension of their reproductive season. The aim of the study presented was to identify genes associated with the reproductive longevity and egg quality. The experiment was performed on 120 layers (cross Hisex Brown) allotted to two treatments, with conditionally high (treatment 1) and low (treatment 2) reproductive longevity. Morphological blood parameters and gene expression in the ovary (by method RNA-SEQ) were determined. In treatment 2 the significant (p<0.05) trend to decreased concentrations of red blood cells (2.22±0.18 106/μL vs. 2.40±0.12 in treatment 1) and hemoglobin (83.00±13.74 g/L vs. 104.67±5.44 in treatment 1) was found. Analysis of differential gene expression in the ovary revealed candidate genes (vtg, GRB10, SGK1, ESR1, ULK1, IGF2, 4EBP1, S6K1, mTOR, PKC, RHO, FSHR) which could be used as markers for the selection of layers with improved reproductive potential.
